Japan Researchers Develop 3D Jawbone Organoids Using Human-Induced Stem Cells
(MENAFN) In a scientific first, Japanese researchers have successfully developed three-dimensional jawbone-like organoids using human-induced pluripotent stem (iPS) cells, according to media on Tuesday.
The pioneering study, led by a team at Kyoto University, demonstrated that once transplanted into mice, these lab-grown organoids matured into fully developed bone tissue.
The breakthrough could open new frontiers in regenerative medicine and pharmaceutical research, with the team noting that their approach has the potential for real-world clinical applications.
Published in July in the online edition of Nature Biomedical Engineering, the research tackles a challenge long considered formidable: replicating the complex structure of human jawbones. Unlike other bones in the body, the jawbone follows a unique developmental path, and previous technology had fallen short in mimicking the dense cellular network essential to its formation.
To overcome these hurdles, scientists cultured human iPS cells, carefully guiding them to form cellular aggregates capable of differentiating into jawbone tissue.
The Kyoto University team indicated that their technique holds strong potential for future use in both regenerative therapies and pharmaceutical development.
Legal Disclaimer:
MENAFN provides the
information “as is” without warranty of any kind. We do not accept
any responsibility or liability for the accuracy, content, images,
videos, licenses, completeness, legality, or reliability of the information
contained in this article. If you have any complaints or copyright
issues related to this article, kindly contact the provider above.
Legal Disclaimer:
EIN Presswire provides this news content "as is" without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above.
